Demand is high from patients with osteoarthritis, meniscus tears and other maladies, but studies haven’t reached firm conclusions yet
Critical for human development and health, neural crest cells arise early in the development of vertebrates. They migrate extensively inside the embryo, and differentiate to give rise to a wide array of diverse derivatives. Accessing these cells, however, is difficult. Work done by a research team now provides a fast, simple and cost-effective method to generate neural crest cells, facilitating research in basic sciences and clinical applications alike.
Injury to the anterior cruciate ligament (ACL) in the knee frequently leads to early-onset osteoarthritis, a painful condition that can occur even if the patient has undergone ACL reconstruction to prevent its onset. A new review looks at the ability of two different reconstruction techniques to restore normal knee motion and potentially slow degenerative changes.